Ohio State Navbar

Research

Participate in Clinical Trial or Research Study


Thank you for considering participation in a research study. Please contact us at SportsMedResearch@osumc.edu for more information on any of the trials listed below.

 

Sports Medicine Clinical Trials

Study Name Overview
VENUS (Verifying the Effectiveness of the NUsurface® System) Clinical Investigation The NUsurface Meniscus Implant is a Polycarbonate-Urethane (PCU)-based device reinforced with high tensile Ultra High Molecular Weight Polyethylene (UHMWPE) fibers. This multi-center, prospective, randomized, interventional clinical study is to evaluate the safety and effectiveness of the NUsurface device compared to the Standard of Care for patients whose medial meniscus may have had tears or degeneration requiring medical or surgical treatment.
   
Mechanical Debridement vs. Radiofrequency-Based Debridement This study evaluates changes in clinical and imaging outcomes following arthroscopic treatment of a single medial femoral chondral lesion plus partial medial meniscectomy by Radiofrequency-based debridement or Mechanical Debridement in subjects ≥ eighteen (18) years of age. Download brochure.
   
Knee Creations SCP®

This observational cohort follow-up study seeks to understand the post-operative outcomes of subjects choosing to undergo the Subchondroplasty™ (SCP™) procedure (a minimally invasive procedure to treats bone defects in the knee associated with bone marrow lesions (BMLs)).

   
NOVOCART® 3D compared to Microfracture

Novocart® 3D is a cellular implant system where small amount of knee cartilage is removed in a an initial surgery, cleaned and "grown" on a 3-dimensional sponge-like scaffold and then implanted into the damaged area in a second surgery approximately 3 weeks later. This Phase 3 prospective, randomized, partially blinded multi-center study measures the safety and efficacy of Novacart compared to Microfracture.

   
NeoCart® compared to Microfracture This investigational study is testing the safety and performance of a new tissue implant called NeoCart®. NeoCart is produced from a small amount of your own healthy knee cartilage (about the size of a pea).
   
Prospective Database of First Time Patellar Dislocations Patellar dislocations are debilitating injuries that frequently affect young, active patients. In spite of the relatively high incidence of this condition, significant controversy remains regarding the ideal treatment protocol.  This study evaluates patients following their treatment for patellar dislocation to help in future treatments for those with the same condition.
   
Multi-center Orthopaedic Outcomes Network (MOON) ACL Study This multi-year study gathers data on the knee before, during and after ACL reconstruction in order to determine what factors may help or hinder the success of an ACL reconstruction. If you have been diagnosed with an ACL tear and are planning on having an ACL reconstruction, you may be eligible to participate. 
   
Database for Hip Surgery Patients This multi-disciplinary effort by clinicians and researchers to better understand outcomes after surgery for common and painful hip conditions follows individuals over several years to determine which factors predict both short- and long-term function. This information will be used to improve patient outcomes through evidence-based care.
   
Joint Health Assessment Study Degenerative disease of the knee joint is an increasingly common condition. Cases of advanced joint degeneration lead to significant disability and often require invasive, expensive treatments. This study evaluates normal and injured knees of patients in different age groups and sexes to determine the value of certain pictures taken by a Magnetic Resonance Image (MRI) machine. 
   

 

Sports Medicine Biodynamics Lab

Study Overview
Markers of Disease and Disability following Hip Arthroscopy for Femoroacetabular Impingement (FAI)

Individuals who have undergone hip arthroscopy to address painful hip impingement will undergo a series of clinical testing, 3-dimensional motion analysis, and magnetic resonance imaging (MRI). The observational study seeks to identify factors related to poor outcomes after surgery so that we can develop the most effective treatment strategies.

   
Multi-Faceted Approach to Modeling ACL Injury Mechanisms Athletes who participate in pivoting, cutting, and jumping sports have a greater chance of suffering an ACL injury compared to most other athletes. The purpose of this study is to develop new, low-cost strategies for identifying athletes at risk of anterior cruciate ligament (ACL) injury. Healthy participants will undergo 3D motion analysis using skin-mounted muscle activity monitoring known as electromyography (EMG) and magnetic resonance imaging (MRI) of the knee and leg. By creating a computer model of participant's knees, we will be able to more accurately describe the effect of the way the participant moves during athletic tasks on their risk of injury.  
   
Mediators of Exercise Driven Musculoskeletal Health Physical inactivity is a major cause for the onset and progression of bone and muscle disorders/diseases, suggesting that the human body regulates bone and muscle health together as one. Research has shown that exercise can help to prevent bone loss and strengthen bones and muscles, yet exercise is not extensively used as a therapy. In this study, we are hoping to uncover how exercise regulates bone and muscle health. Using this information, we might then be able to measure how exercise is increasing health or how to best use exercise in specific ways as therapy to increase health. 

 

 

OSU Asthma Center

There are a number of clinical trials underway that address treatment of asthma.  They are currently recruiting participants for a study of Soy and Asthma and whether treatment of sinus problems reduces asthma.

Please go to the following website for details on all the studies.   http://asthma.osu.edu/10555.cfm